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MK-4827 Racemate
CAS No. 1038915-75-1
MK-4827 Racemate( Niraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide )
Catalog No. M27657 CAS No. 1038915-75-1
MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 57 | Get Quote |
|
| 5MG | 80 | Get Quote |
|
| 10MG | 140 | Get Quote |
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| 25MG | 267 | Get Quote |
|
| 50MG | 466 | Get Quote |
|
| 100MG | 628 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMK-4827 Racemate
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NoteResearch use only, not for human use.
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Brief DescriptionMK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
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DescriptionMK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
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In Vitro——
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In Vivo——
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SynonymsNiraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
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PathwayCell Cycle/DNA Damage
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TargetPARP
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number1038915-75-1
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Formula Weight320.396
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Molecular FormulaC19H20N4O
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Purity>98% (HPLC)
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Solubility——
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SMILESNC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C1CCCNC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.
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MK-4827 hydrochlorid...
A highly potent PARP inhibitor with IC50 of 3.8 nM/2.1 nM for PARP1/PARP2.
